Today, the results of our work interpreting the genomes of primary triple negative breast cancers appeared in Nature: “The clonal and mutational evolution spectrum of primary triple-negative breast cancers”. Many many thanks to all of the members of the lab for dedication and hard work on this project.

Andrew Roth, Ryan Morin, Jiarui Ding, Anamaria Crisan, Gavin Ha, Ryan Giuliany, Ali Bashashati, Martin Hirst, Gulisa Turashvili, Arusha Oloumi, Marco A. Marra, Samuel Aparicio and Sohrab P. Shah. JointSNVMix : A Probabilistic Model For Accurate Detection Of Somatic Mutations In Normal/Tumour Paired Next Generation Sequencing Data. Bioinformatics. 2012 doi: 10.1093/bioinformatics/bts053 SOFTWARE

Jiarui Ding; Ali Bashashati; Andrew Roth; Arusha Oloumi; Kane Tse; Thomas Zeng; Gholamreza Haffari; Martin Hirst; Marco A. Marra; Anne Condon; Samuel Aparicio; Sohrab P. Shah. “Feature based classifiers for somatic mutation detection in tumour-normal paired sequencing data.” Bioinformatics 2011; doi: 10.1093/bioinformatics/btr629 [PDF] [SOFTWARE]